Lisenka Vissers

Lisenka Vissers 2018Dr. Lisenka Vissers is head of the Translational Genomics team, which focuses on the evaluation and optimization of novel genomic technologies for diagnostic implementation. The team exists of 2 assistant professors, 4 laboratory technicians and 3 bioinformaticians.

 

Her research has focused on the optimization and large-scale implementation of high-throughput, state-of-the art genomic technologies for the study of human genetic disease. During her PhD project, she has demonstrated record of productive and successful research leading to improved patient care by the implementation of array CGH for patients with intellectual disability (ID) into routine diagnostics as well as by the identification of novel syndromes and disease-causing genes.

In 2008, Lisenka obtained a veni grant and used this to apply next generation sequencing to identify novel disease genes. She was the first to use family-based whole exome sequencing for the identification of de novo mutations creating a paradigm shift in the field of medical genetics. Also, the achieved results provided a founding base to assess the diagnostic yield of exome sequencing in a routine diagnostic setting. The next frontiers in routine clinical diagnosis will, amongst others, include the implementation of whole genome sequencing as well as improving the clinical interpretation of (non-coding) genetic variation.

 

Our team

Our team consists of passionate and experienced people

 

Ms. Helger Yntema, PhD Head Genome Diagnostics, clinical laboratory geneticist
Marcel Nelen, PhD Deputy head Genome Diagnostics, Head team Core Genome Analysis Laboratory, clinical laboratory geneticist
Erik-Jan Kamsteeg, PhD Head team Muscular, Neurological, Renal & Sensory disorders, clinical laboratory geneticist
Dominique Smeets, PhD Head team Fertility & Pregnancy, clinical laboratory geneticist
Ms. Nicole de Leeuw, PhD Head team Intellectual Disability, Multiple Congenital Abnormalities & Endocrine disorders, clinical laboratory geneticist
Ms. Marjolijn Ligtenberg, PhD Head team Laboratory Tumor Genetics, associate professor Tumor Genetics, clinical laboratory geneticist
Lisenka Vissers, PhD Head team Translational Genomics, molecular geneticist
Hans Scheffer, PhD Associate professor clinical molecular genetics, clinical laboratory geneticist
Ms. Brigitte Faas, PhD Clinical laboratory geneticist
Rolph Pfundt, PhD Clinical laboratory geneticist
Ms. Marian Stevens-Kroef, PhD Clinical laboratory geneticist
Ms. Annet Simons, PhD Clinical laboratory geneticist
Arjen Mensenkamp, PhD Clinical laboratory geneticist
Ms. Daniel Olde Weghuis, PhD Clinical cytogeneticist
Ms. Tuula Rinne, PhD Clinical laboratory geneticist
Ms. Dorien Lugtenberg, PhD Clinical laboratory geneticist
Christian Gilissen, PhD Bioinformatician
Ms. Kornelia Neveling, PhD Molecular geneticist